Endocrine Abstracts

A 33-year-old Belgian woman was referred in June 2006 to our Metabolic Bone Diseases Clinic for recent vertebral fractures. X-Rays showed a 3-level severe compression fractures with collapse of the superior endplates of D11, D12 and L1. DXA showed significantly decreased lumbar spine (LS) and femoral neck (FN) Z-scores, at −3.1 and −2.5, respectively.She was complaining of severe back pain, muscle weakness, cognitive dysfunction, anxiety and ...

Osteoporosis is a major public health problem that is responsible for a considerable morbidity, mortality and health care costs. Evaluation of fracture risk is essential to select patients who will benefit most of interventional strategies. Most prospective cohort studies, with fracture outcomes, rely on participant self-report as the main or only source of information on fracture incidence. Systematic validation by screening of medical files is time-consuming, costly and almo...

In large population-based epidemiological studies of osteoporotic fractures, self-report is an important way of obtaining information. However, this method is subject to errors of recall and may result in misclassification of fracture status. Surprisingly, the accuracy of self-reported fractures has only rarely been assessed. The purpose of our study was to assess the accuracy of self-reported fractures in the FRISBEE cohort (Brussels, Belgium) of 3560 postmenopausal, aged 60&...